Publications
Publication Author: Essigmann, John M
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2018Essigmann, John M,Fedeles, Bogdan I,
Impact of DNA lesion repair, replication and formation on the mutational spectra of environmental carcinogens: Aflatoxin B as a case study.
DNA Repair (Amst).2018;12-22. -
2017Croy, Robert G,Essigmann, John M,Egner, Patricia A,Groopman, John D,Chawanthayatham, Supawadee,Vartanian, Vladimir,Minko, Irina G,Lin, Ying-Chih,Earley, Lauriel F,Makar, Rosemary,Eng, Jennifer R,Camp, Matthew T,Li, Liang,Stone, Michael P,Lasarev, Michael R,McCullough, Amanda K,Lloyd, R Stephen,
NEIL1 protects against aflatoxin-induced hepatocellular carcinoma in mice.
Proc Natl Acad Sci U S A.2017;(16)4207-4212. -
2017Li, Deyu,Essigmann, John M,Singh, Vipender,Fedeles, Bogdan I,Chen, Fangyi,Tang, Qi,Bian, Ke,Humulock, Zachary T,
Oncometabolites d- and l-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological Conditions.
Chem Res Toxicol.2017;(4)1102-1110. -
2017Essigmann, John M,Chang, Shiou-Chi,Wu, Jie,Seneviratne, Uthpala I,Tretyakova, Natalia,
1,3-Butadiene-Induced Adenine DNA Adducts Are Genotoxic but Only Weakly Mutagenic When Replicated in Escherichia coli of Various Repair and Replication Backgrounds.
Chem Res Toxicol.2017;(5)1230-1239. -
2017Croy, Robert G,Essigmann, John M,Fedeles, Bogdan I,Egner, Patricia A,Groopman, John D,Chawanthayatham, Supawadee,Slocum, Stephen L,Satayavivad, Jutamaad,Sriwattanapong, Kanokwan,
Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver.
Toxicol Sci.2017;(1)173-179. -
2018Essigmann, John M,Fedeles, Bogdan I,Tajai, Preechaya,Suriyo, Tawit,Kanitwithayanun, Jantamas,Satayavivad, Jutamaad,
An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity
Free Radical Biology and Medicine.2018; -
2017Croy, Robert G,Essigmann, John M,Fedeles, Bogdan I,Chawanthayatham, Supawadee,Wogan, Gerald N.,
Early detection of the aflatoxin B1 mutational fingerprint: A diagnostic tool for liver cancer
Molecular & Cellular Oncology.2017;(4) -
2017Croy, Robert G,Essigmann, John M,Fedeles, Bogdan I,Wogan, Gerald N,Chawanthayatham, Supawadee,Levine, Stuart S,Valentine, Charles C,Fox, Edward J,Loeb, Lawrence A,Slocum, Stephen L,
Mutational spectra of aflatoxin B1 in vivo establish biomarkers of exposure for human hepatocellular carcinoma
PNAS.2017;(15)E3101-E3109. -
2016Li, Deyu,Essigmann, John M,Yang, Xuedong,Drennan, Catherine L,Jost, Marco,Chen, Fangyi,Tang, Qi,Bian, Ke,Humulock, Zachary T,
Adaptive Response Enzyme AlkB Preferentially Repairs 1-Methylguanine and 3-Methylthymine Adducts in Double-Stranded DNA.
Chem Res Toxicol.2016;(4)687-93. -
2015Li, Deyu,Essigmann, John M,Singh, Vipender,Fedeles, Bogdan I,Delaney, James C,Chang, Shiou-Chi,Yau, Emily,Freudenthal, Bret D,Wilson, Samuel H,
Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer.
Proc Natl Acad Sci U S A.2015;(33)E4571-80.